By Pradyot Patnaik
The definitive consultant to the dangerous houses of chemical compounds
Correlating chemical constitution with toxicity to people and the surroundings, and the chemical constitution of compounds to their dangerous houses, A accomplished consultant to the detrimental homes of chemicals, 3rd Edition permits clients to evaluate the toxicity of a substance even if no experimental info exists. hence, it bridges the distance among unsafe fabrics and chemistry. widely up to date and increased, this reference:
- Examines organics, metals and inorganics, commercial solvents, universal gases, particulates, explosives, and radioactive ingredients, overlaying every thing from toxicity and carcinogenicity to flammability and explosive reactivity to dealing with and disposal practices
- Arranges dangerous chemicals in keeping with their chemical constructions and sensible teams for simple reference
- Includes up to date details at the poisonous, flammable, and explosive houses of chemical substances
- Covers extra metals within the chapters on poisonous and reactive metals
- Updates the edge publicity limits within the office air for a few substances
- Features the most recent details on commercial solvents and poisonous and flammable gases
- Includes quite a few tables, formulation, and a word list for fast reference
since it presents info that permits people with a chemistry heritage to accomplish exams with no previous info, this complete reference appeals to chemists, chemical engineers, toxicologists, and forensic scientists, in addition to commercial hygienists, occupational physicians, Hazmat pros, and others in comparable fields.
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Extra resources for A comprehensive guide to the hazardous properties of chemical substances
Lowermolecular-weight alcohols, aldehydes, ketones, carboxylic acids, aliphatic amines, amides, nitriles, and many other functional groups dissolve in water. The solubility, ! 2AgC (aq) C CrO24 (aq) 0 C2S 2S 0 CS S however, decreases with an increase in the carbon chain length. The addition of double and triple bonds to the molecule increases the water solubility. Also, ring formation for a given carbon number increases the solubility. For alkanes, alkenes, and alkynes, types of hydrocarbons (all of which have very low solubility in water) branching increases the solubility; while for aromatics and cycloalkanes, there is no effect from branching.
Ethanol is a classic example, causing both acute and chronic lesions. It induces large droplets of fat in the cell. On the other hand, substances such as tetracycline and phosphorus produce many A Comprehensive Guide to the Hazardous Properties of Chemical Substances, by Pradyot Patnaik Copyright © 2007 John Wiley & Sons, Inc. 26 KIDNEY INJURY: NEPHROTOXICANTS small fat droplets in the cells, causing acute lesions. Among the two common mechanisms of steatosis, one involves an increased formation of triglyceride and other lipid moieties, while the other mechanism manifests an impairment in the release of hepatic triglyceride to the plasma.
Pulmonary Pertaining to the lungs. Pulmonary edema Excess ﬂuid in the lungs, caused by irritants that injure the pulmonary epithelium. Such conditions can affect oxygen uptake, causing death. Receptor Binding site that has a high afﬁnity for a particular ligand. Receptors interact with biologically endogenous ligands, facilitating intracellular communication. Many chemicals interact with receptors, producing a variety of toxic effects. Renal Pertaining to the kidney. Routes of entry There are several routes by which a chemical can enter the body.
A comprehensive guide to the hazardous properties of chemical substances by Pradyot Patnaik