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By L. R. Haaheim, J. R. Pattison, R. J. Whitley

ISBN-10: 0471950971

ISBN-13: 9780471950974

This moment variation of A functional consultant to medical Virology is a realistic, hugely illustrated, fast reference advisor to medical virology. It brings jointly the necessities of the topic in a unique and informative variety, describing in flip the medical good points, the indicators and indicators of every of the viral illnesses, in addition to summarising the epidemiology, laboratory prognosis and remedy in each one case. This ebook additionally comprises normal chapters on type, prognosis of an infection, antiviral medicinal drugs, vaccines and diversified scientific syndromes.
Key Features:* bankruptcy summaries for speedy reference* comic strip illustrations* complete insurance* transparent and concise format
Each bankruptcy is straightforward to learn and good organised, making sure that this is often a useful textbook for all scientific, biomedical, microbiology and utilized biology scholars. moreover, it offers a good reference for nurses, occupational wellbeing and fitness and an infection keep an eye on departments, public healthiness and diagnostic laboratories.

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Extra info for A Practical Guide to Clinical Virology

Sample text

Unfortunately the phosphorylation to the active triphosphate occurs not only in virus-infected cells but also in normal cells, and this explains the side-effects of the drug. In contrast, as we have noted above, aciclovir triphosphate is only present in herpes-infected cells. A number of dideoxynucleoside analogues (ddI, ddC, 3TC, D4T) have been clinically evaluated and although they all exert antiviral effects nevertheless they also have side-effects, each specific to the compound in question. Also effective are non-nucleoside analogue inhibitors of viral reverse transcriptase and particularly inhibitors of other viral target enzymes such as protease.

Blood samples for demonstration of seroconversion or titre rise (paired sera) are taken 1–3 weeks apart, depending on the time of exposure or onset of symptoms. INTERPRETATION OF RESULTS To achieve the full benefit of virological tests, appropriate specimens must be taken at the optimum time and must be transported to the laboratory as recommended. In the laboratory, the virologist will decide on appropriate tests on the basis of the information given by the clinician. This information will also be important for the interpretation of the laboratory findings.

This ambitious global effort is directed by the WHO. Modern science has provided a better understanding of the fine structures of virus particles, thus allowing the identification and subsequent large-scale production of the most useful parts of the infectious agent for vaccine use. This methodology has now been put to good practical use for the preparation of hepatitis B vaccine using cloned DNA expressed in yeast cells to produce HBsAg. This was a giant leap from the earlier method of purifying HBsAg from the blood of hepatitis carriers.

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A Practical Guide to Clinical Virology by L. R. Haaheim, J. R. Pattison, R. J. Whitley

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